Hi
For targeted re-sequenced data, can we do variant calling using HaplotypeCaller in gVCF mode followed by using GenotypeGVCFs for joint genotyping ?
Would the following best practices work for targeted re-sequencing as well , except for VQSR as for targted resequencing GATK advices another way of filtering. https://www.broadinstitute.org/gatk/guide/best-practices?bpm=DNAseq
Thanks, Tinu